Imunofan

$27.00
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Product Description

Imunofan - detoxification, hepatoprotective, antioxidant, immunomodulatory.

The drug has an immunoregulatory, detoxifying, hepatoprotective effect and causes the inactivation of free radical and peroxide compounds. Corrects the state of the immune system, restores the balance of oxidative-antioxidant reactions of the body and helps to overcome the multidrug resistance of tumor cells mediated by the proteins of the transmembrane transport pump of the cell.

The action of the drug begins to develop within 2-3 hours (fast phase) and lasts up to 4 months (medium and slow phases).

During the fast phase (duration - up to 2-3 days), the detoxification effect is manifested primarily - the antioxidant defense of the body is enhanced due to stimulation of the production of ceruloplasmin, lactoferrin, catalase activity; the drug normalizes lipid peroxidation, inhibits the breakdown of cell membrane phospholipids and the synthesis of arachidonic acid, followed by a decrease in blood cholesterol and the production of inflammatory mediators. In case of toxic and infectious liver damage, the drug prevents cytolysis, reduces the activity of transaminases and the level of bilirubin in the blood serum.

During the middle phase (begins in 2–3 days, duration - up to 7–10 days), the reactions of phagocytosis and death of intracellular bacteria and viruses intensify.

During the slow phase (begins to develop on 7–10 days, duration up to 4 months), the immunoregulatory effect of Imunofan is manifested - the restoration of impaired indicators of cellular and humoral immunity. During this period, the normalization of the immunoregulatory index is observed, an increase in the production of specific antibodies is noted. The effect of the drug on the production of specific antiviral and antibacterial antibodies is equivalent to the action of therapeutic vaccines. Unlike the latter, the drug does not significantly affect the production of IgE class reagin antibodies and does not enhance the immediate hypersensitivity reaction; Imunofan stimulates the formation of IgA in case of congenital insufficiency.

Imunofan effectively suppresses the multidrug resistance of tumor cells and increases their sensitivity to chemotherapeutic drugs.

IMUNOFAN INDICATIONS FOR USE

For adults and children over 2 years of age (prevention and treatment):
- Immunodeficiency and toxic conditions;
- Chronic inflammatory diseases of various etiologies.

For adults - as an adjuvant for vaccination against bacterial and viral infections.

Pregnancy and lactation
Due to insufficient knowledge should be used with caution during pregnancy and lactation.

Contraindications
Hypersensitivity; children under 2 years old.

Side effects
Perhaps: individual intolerance, allergic reactions.

Interaction
Increases the effectiveness of other types of drug therapy: the use of imunofan helps to overcome resistance to glucocorticosteroid therapy.

The purpose of the drug is possible in combination with anti-inflammatory steroid and non-steroidal anti-inflammatory drugs.

INSTRUCTION FOR USE

Subcutaneous or intramuscular injection. Single and daily dose - 50 mcg.

In the treatment of cancer patients in the scheme of radical combined treatment (chemo-radiation therapy and surgery)
Once, daily, the course of treatment is 8-10 injections before chemo-radiation therapy and surgery, followed by the continuation of the course throughout the treatment period.

In patients with a common tumor process (stage III-IV) of various localization in the form of complex or symptomatic therapy
Once, daily, the course of treatment is 8-10 injections, with a break of 15-20 days and the repetition of courses throughout the entire period of subsequent treatment.

In children with malignant diseases of the hematopoietic and lymphoid tissue
Once a day, daily, the course of treatment is 10-20 injections. The appointment of the drug should be carried out throughout the course of chemo-radiation therapy and after the end of the course to prevent the development of toxicosis.

In the complex therapy of children with paplomatosis of the larynx and oropharynx
1 time a day, daily, a course of treatment of 10 injections.

For opportunistic infections (cytomegalovirus and herpetic infections, toxoplasmosis, chlamydia, pneumocystosis, cryptosporidiosis)
Once a day, daily, the course of treatment is 15-20 injections.

In the complex treatment of HIV infection
Once a day, daily, the course of treatment is 15-20 injections.

With chronic viral hepatitis and chronic brucellosis
Once a day, daily, the course of treatment is 15-20 injections, to prevent relapse, repeated courses should be carried out after 2-3 months.

With diphtheria
Once a day, daily, the course of treatment is 8-10 injections. With diphtheria bacteriocarrier - 1 time after 3 days - 3-5 injections.

In the treatment of burns of the III-IV degree with the phenomena of toxemia, septicotoxemia, in surgical patients with septic

endocarditis, long-term non-healing limb wounds, purulent-septic complications
Once a day, daily, the course of treatment is 7-10 injections, if necessary, the drug should be continued up to 20 injections.

With broncho-obstructive syndrome, cholecystopancreatitis, rheumatoid arthritis
1 time after 3 days, the course of treatment is 8-10 injections, if necessary, the course should be continued up to 20 injections with the same interval.

In the treatment of psoriasis
1- once a day, daily, a course of treatment of 15-20 injections.

In the complex treatment of adults and children with inflammatory eye diseases
In case of damage to the anterior parts of the eye (keratitis, keratouveitis), 0.5 ml subconjunctival or in combination with intramuscular injection, 1 time per day daily, the course of treatment is 7-10 injections.

When mainly the posterior parts of the eye are affected (peripheral, posterior uveitis, retinovasculitis) and generalized inflammatory processes, 0.5-1.0 ml parabulbar in combination with intramuscular injection, 1 time per day, daily, the course of treatment is 15-20 injections.

In adults, in the scheme of vaccination
Once a day vaccination.

Intranasally
Remove the protective cap from the spray gun.
Before the first use, fill the dosing pump by pressing the wide rim of the sprayer 3-4 times.
Insert the nebulizer into the nasal passage with the head upright.
Press the wide bezel of the spray gun once as far as it will go.
In 1 dose of the drug contains 50 μg of immunofan. The daily dose should not exceed 200 mcg.

In the complex treatment of acute and chronic infectious and inflammatory diseases accompanied by symptoms of intoxication and immunodeficiency
Assign 1 dose (50 mcg) in each nasal passage 2 times a day, daily for 10-15 days.

For opportunistic infections (cytomegalovirus and herpetic infections, toxoplasmosis, chlamydia, pneumocystosis, cryptosporidiosis)
1 dose (50 mcg) in each nasal passage 2 times a day, daily, treatment 10-15 days. If necessary, the course may be repeated after 2-4 weeks.

With chronic viral hepatitis and chronic brucellosis
At 1 dose (50 mcg) in each nasal passage 1 time per day, daily, the course of treatment is 10-15 days, to prevent relapse, repeated courses should be taken after 4-6 months.

In the treatment regimen for HIV patients
1 dose (50 mcg) in each nasal passage 1 time per day, daily, for 10-15 days. If necessary, the course may be repeated after 2-4 weeks.

In the treatment of cancer patients in the scheme of radical combined treatment (chemo-radiation therapy and surgery)
1 dose (50 mcg) in each nasal passage 1 time per day, daily, for 8-10 days before chemo-radiation therapy and surgery, followed by the continuation of the course throughout the treatment period.

In patients with a common tumor process (stage III-IV) of various localization in terms of complex or symptomatic therapy
1 dose (50 mcg) in each nasal passage 1 time per day, daily, for 8-10 days. If necessary and the presence of pronounced phenomena of toxicosis, a repeated course is recommended.

Rectally

Single dose and daily - 100 mcg (0.1 mg) 1 suppository.

In the treatment of cancer patients in the scheme of radical combined treatment (chemo-radiation therapy and surgery)
Once, daily, the course of treatment is 8 to 10 suppositories before chemo-radiation therapy and surgery, followed by the continuation of the course throughout the treatment period.

In patients with a common tumor process (stage III - IV) of various localization in the form of complex or symptomatic therapy
Once, daily, the course of treatment is 8 to 10 suppositories, with a break of 15-20 days and the repetition of courses throughout the entire period of subsequent treatment.

In children with malignant diseases of the hematopoietic and lymphoid tissue
Once a day, daily, the course of treatment is 10-20 suppositories. The appointment of the drug should be carried out throughout the course of chemo-radiation therapy and after the end of the course to prevent the development of toxicosis.

In the complex therapy of children with papillomatosis of the larynx and oropharynx
Once a day, daily, a course of treatment of 10 suppositories.

For opportunistic infections (cytomegalovirus and herpetic infections, toxoplasmosis, chlamydia, pneumocystosis, cryptosporidiosis)
Once a day, daily, the course of treatment is 15 to 20 suppositories.

In the complex treatment of HIV infection
Once a day, daily, the course of treatment is 15 to 20 suppositories. If necessary, repeat courses should be given after 2-4 weeks.

With chronic viral hepatitis and chronic brucellosis
Once a day, daily, the course of treatment is 15 to 20 suppositories, to prevent relapse, repeated courses should be taken after 2 to 3 months.

With diphtheria
Once a day, daily, the course of treatment is 8 to 10 suppositories. With diphtheria bacteriocarrier - 1 time after 3 days - 3-5 suppositories.

In the treatment of burns of the III-IV degree with the effects of toxemia, septicotoxemia, in surgical patients with septic endocarditis, long-term healing of limb wounds, purulent-septic complications
Once a day, daily, the course of treatment is 7 to 10 suppositories, if necessary, the course of the drug should be continued up to 20 suppositories.

With broncho-obstructive syndrome, cholecystopancreatitis, rheumatoid arthritis
1 time after 3 days, the course of treatment is 8 to 10 suppositories, if necessary, the course should be continued up to 20 suppositories with the same interval.

In the treatment of psoriasis
Once a day, daily, the course of treatment is 15 to 20 suppositories.

In adults, in the scheme of vaccination
Once a day vaccination.

Special instructions
As a result of activation of phagocytosis, a short-term exacerbation of foci of chronic inflammation, supported by the persistence of viral or bacterial antigens, is possible.

Storage conditions
In a dry, dark place at a temperature of 2–10 ° C

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