1 tablet contains:
orthosiphon stamen (orthosiphon stamineus benth) 80 mg;
bearberry ordinary (bearberry) 80 mg;
Cranberry (cranberry juice) 80 mg;
corn stigmas (com silk) 80 mg;
horsetail (equiseum) 40 mg;
common blueberries (dandelion) 40 mg;
medicinal dandelion (bilberry common) 40 mg;
magnesium citrate 20 mg.
Orthosiphon stamen (orthosiphon stamineus benth). Orthosiphon leaves contain glycoside orthosiphonin (0.01%), alkaloids, fatty oils (2.7%), tartaric acid (1.5%), citric acid, essential oils (0.2 - 0.66%), saponins after saponification of which α-amyrin, β-sitosterol and tannin are secreted. In medicine, orthosiphon preparations are used as a diuretic in acute and chronic kidney diseases, accompanied by edema, albuminuria, azotemia, and kidney stone disease. The diuretic effect is accompanied by increased excretion of urea, uric acid and chlorides from the body. Orthosiphon increases the secretion of the gastric glands and free hydrochloric acid. Orthosiphon has low toxicity, has a large breadth of therapeutic effect and does not cause side effects with prolonged use.
Bearberry (Arctostaphylos uva-ursi L.). Bearberry leaves contain flavanoids (quercetin, isocvercetin, myricitrin, hyperoside, miracetin), organic acids (malic, protocatechol, formic), tannins of the pyrogall group, glycosides arbutin and methylarbutin. All these active ingredients form the basis of the chemical composition of bearberry ordinary (bear’s ear).
Bearberry galenic preparations have anti-inflammatory, antimicrobial and diuretic properties. The anti-inflammatory effect of the drug is due to the content of a large number of tannins. The antimicrobial property of the plant is associated with the glycoside arbutin, which, under the influence of the arbutase enzyme contained in the leaves, is split into free hydroquinone and glucose. The second glycoside methylarbutin during hydrolysis, cleaving methyl alcohol, releases hydroquinone. The antiseptic properties of bearberry leaves are due to the antimicrobial and locally irritating effect of hydroquinone, which, excreted in the urine, irritates the kidney tissue through the kidneys and increases urination.
Cranberries (cranberry juice). Contains: organic acids (including benzoic), pectin, triterpene compounds, flavanoids, anthocyanins, catechins, tannins, vitamin C, carotenoids. Cranberries are also rich in potassium and iron. Cranberries have antimicrobial properties, including against staphillococci, streptococci, Escherichia coli, Proteus, and cholera pathogens. An antifungal effect is noted. In addition, cranberry berries enhance the action of antibiotics, nitrofurans and sulfa drugs, in particular in the treatment of pyelonephritis and gynecological inflammatory diseases. Currently, cranberries are recommended for use in urinary tract infections. An interesting property of cranberry fruit extract was discovered - to counteract the adhesion and adhesion of bacteria to the cells of the mucous membrane of the bladder, which prevents them from forming colonies. One of the components contained in cranberry fruits, ursulic acid, has a strong diuretic effect and prevents the formation of kidney stones.
Horsetail (equiseum) is used as a diuretic, hemostatic, hypotensive, anti-inflammatory, anti-sclerotic. 5-glucoside-luteolin isolated from field horsetail has antimicrobial and anti-inflammatory properties. Horsetail extract optimizes water-salt metabolism and improves the condition with diseases of the urinary system. With uric acid diathesis, the active substances of the horsetail keep in the urine the balance between colloids and crystalloids and, thereby, delay the formation of urinary stones, especially oxalates. Silicon compounds of the plant play an important role in the processes of metabolism and functional activity of the connective tissue of joints and walls of blood vessels.
Corn stigmas (Zea mays L - com silk). Bitter glycoside substances 1.15%, saponins 3.18%, fatty oils 2.5%, cryptosanthin, ascorbic and pantothenic acid, vitamin K, inositol, sitosterol, stigmasterol were found in corn stigmas. Corn seeds contain starch 61.2%, corn oil, a large number of pentosans 7.4%, biotin, nicotinic and pantothenic acid, quercetin, isocvercetin and others. Corn stigmas are used as a diuretic, choleretic, hemostatic agent in the treatment of cholecystitis, hepatitis, with urological diseases, urolithiasis, jade, edema, as well as with helminthic invasions.
Blueberry (Vaccinium mytillus). Blueberry leaves are rich in inulin, flavonoids, anthocyanins. The fruits contain carbohydrates, organic acids, vitamins (C, B1, B2, P, PP), carotene, a high amount of phenoxy acids (quinic, coffee, chlorogenic), manganese and iron compounds. Blueberries are known as increasing the body's immunity, its resistance to stress, hemostatic, hematopoietic, vasodilating, astringent, choleretic and diuretic.
Medicinal dandelion (Taraxacum officinale). Dandelion roots contain taraxacin up to 10%, triterpene compounds (taraxerol, taraxasterol), sterols (r-sitosterol, stigmasterol), flavanoids (cosmosine, luteolin-7-glucoside), inulin up to 24%, fatty oils, sucrose up to 20%, 15% proteins, carotene, tannins, essential oils. Dandelion roots contain alcohols, saponins, a significant amount of protein, vitamins C, A, B 2 , nicotinic acid. The content of iron, calcium, manganese and phosphorus found in dandelion leaves is greater than in leafy vegetables. Roots and leaves have anti-inflammatory, choleretic, diuretic, diaphoretic, expectorant, antipyretic, laxative, anti-allergic and anthelmintic effects.
Magnesium citrate maintains the necessary energy level of the whole organism. Recommended for muscle weakness, nervous exhaustion, general fatigue and chronic fatigue syndrome. With a lack of magnesium, potassium is excreted from the body, which leads to fatigue, loss of strength and weakness during heat. In addition, intracellular magnesium is 80-90% in complex with ATP, which is a universal carrier and the main energy accumulator in living cells. Magnesium maintains urine salts in a dissolved state and prevents their deposition. It suppresses stone formation in the kidneys, even in small concentrations inhibits crystallization. Mg 2+ ions in urine bind up to 40% oxalic acid. Prevents precipitation of calcium compounds. It is an antidote for poisoning with salts of heavy metals.
- Acute and chronic inflammatory diseases of the genitourinary organs (urethritis, cystitis, pyelonephritis, vulvitis, vaginitis);
- kidney stones (nephrolithiasis) and bladder stones;
- chronic viral hepatitis;
- nephrotic syndrome;
- arterial hypertension;
- with cardiovascular insufficiency of the II-III degree (together with cardiac glycosides);
- cholecystitis, cirrhosis, ascites, helminthic invasions.
- Hypersensitivity to the components of the drug;
- hyperacid gastritis;
- peptic ulcer of the stomach or duodenum against the background of increased acidity of gastric juice;
- increased blood coagulation.
Novanefron is usually well tolerated.
Rarely: allergic reactions, weakness.
How to take, course of administration and dosage
For free use by the consumer, the norms indicated on the packaging must be observed.
If the drug is prescribed by a doctor, a change in dosage is possible.
1-2 tablets twice daily in the morning and evening.
The duration of treatment is 2-8 weeks.