pancreatin - 0.1 g (25 units).
milk sugar (lactose),
cellacephate (acetylphthalyl cellulose),
titanium dioxide (titanium dioxide),
liquid paraffin (liquid paraffin),
dye azorubine (acid red 2C).
Compensates the insufficiency of exocrine pancreatic function, has a proteolytic, amylolytic and lipolytic effect.
The enzymes that make up Pancreatin (lipase, amylase, trypsin, chymotrypsin) help break down proteins to amino acids, fats to glycerol and fatty acids, starch to dextrins and monosaccharides.
Improves the functional state of the gastrointestinal tract, normalizes digestion processes.
Trypsin inhibits the stimulated secretion of the pancreas, providing an analgesic effect.
Pancreatic enzymes are released from the dosage form in the alkaline environment of the small intestine, because protected from the action of gastric juice by the membrane.
- replacement therapy for exocrine pancreatic insufficiency: chronic pancreatitis, pancreatectomy, post irradiation, dyspepsia, cystic fibrosis;
- flatulence, diarrhea of non-infectious genesis, Remkheld’s syndrome (gastrocardial syndrome);
- violation of the assimilation of food (condition after resection of the stomach and small intestine); to improve the digestion of food in individuals with normal gastrointestinal tract function in case of nutrition errors (eating fatty foods, large amounts of food, irregular nutrition) and with masticatory function disorders, a sedentary lifestyle, prolonged immobilization;
- preparation for x-ray and ultrasound examination of the abdominal organs.
Hypersensitivity to the drug, acute pancreatitis, exacerbation of chronic pancreatitis, children under 6 years old
Allergic reactions. Rarely - diarrhea, constipation, a feeling of discomfort in the stomach, nausea (a causal relationship between the development of these reactions and the action of pancreatin has not been established, since these phenomena relate to symptoms of exocrine pancreatic insufficiency).
With prolonged use in high doses, the development of hyperuricosuria, hyperuricemia is possible. With cystic fibrosis, if the required dose of Pancreatin is exceeded, strictures (fibrotic colonopathy) may develop in the ileocecal section in the ascending colon.
When using Pancreatin in high doses in children, perianal irritation and irritation of the oral mucosa are possible
When using Pancreatin, a decrease in the absorption of iron and folic acid is possible.
The simultaneous use of antacids containing calcium carbonate and / or magnesium hydroxide can lead to a decrease in the effectiveness of pancreatin.
How to take, course of administration and dosage
Inside. The drug is taken during or after a meal, without chewing and drinking with an alkaline liquid (water, fruit juices).
The dose is determined individually depending on the degree of digestion.
Adults usually take 2-4 tablets 3-6 times a day. The maximum daily dose is 16 tablets.
In children over 6 years of age, the drug is used as directed by a doctor. The dose is determined individually. Usually, 1 tablet is prescribed 3 times a day.
The duration of treatment can vary from a few days (if the digestive process is disturbed due to errors in the diet) to several months or years (if constant replacement therapy is necessary).
Symptoms: hyperuricosuria, hyperuricemia. In children - constipation.
Treatment: drug withdrawal, symptomatic therapy.
With cystic fibrosis, the use of Pancreatin in high doses is not recommended due to an increased risk of developing strictures (fibrotic colonopathy).
The dose should be adequate to the amount of enzymes necessary for the absorption of fats, taking into account the quality and quantity of food consumed.