Polyvalent Klebsiella bacteriophage, vials, 20 ml, 4 pcs.

$37.00
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Product Description

Structure

The solution contains:

Active substance:

sterile mixture of purified filtrates of Klebsiella pneumonia phagolysates,

Klebsiella ozaenae,

Klebsiella rhinoscleromatis 10 ml.

Excipients :

 8-hydroxyquinoline sulfate monohydrate 0.0001 g / ml.

pharmachologic effect

The drug causes specific lysis of bacteria Klebsiella pneumoniae, Klebsiella ozaenae, Klebsiella rhinoscleromatis.

Indications

Treatment and prevention of diseases caused by the bacteria Klebsiella pneumoniae, Klebsiella ozaenae, Klebsiella rhinoscleromatis as part of complex therapy:

  • ozena, scleroma;
  • diseases of the gastrointestinal tract (gastroenterocolitis, cholecystitis, pancreatitis, intestinal dysbiosis);
  • inflammatory diseases of newborns and young children (gastroenterocolitis, intestinal dysbiosis, omphalitis, pemphigus, pyoderma, septicemia and septicopyemia of various localization);
  • surgical infections (suppuration of wounds, purulent skin lesions, burns, peritonitis, pleurisy, mastitis, osteomyelitis, abscess);
  • urogenital infections (cystitis, pyelonephritis, urethritis, endometritis, vulvitis, bartholinitis, colpitis, salpingo-oophoritis);
  • purulent-inflammatory diseases of the ear, throat, nose, sinuses, oral cavity, pharynx, larynx, bronchi, lungs and pleura (otitis media, tonsillitis, pharyngitis, laryngitis, stomatitis, periodontitis, sinusitis, frontal sinusitis, bronchitis, pneumonia, pleurisy);
  • post-traumatic conjunctivitis, keratoconjunctivitis, purulent corneal ulcer and iridocyclitis;
  • prevention of nosocomial infections caused by Klebsiella.

Contraindications

Hypersensitivity to the components of the drug.

Side effects

Allergic reactions.

How to take, course of administration and dosage

The drug is used for oral administration (through the mouth), in the form of enemas, applications, irrigation, introduction into the cavity of wounds, vagina, uterus, nose, sinuses, as well as into drained cavities: abscesses, abdominal, pleural, bladder, renal pelvis.

Inside, the drug is taken on an empty stomach 0.5-1 hour before meals.

 

Patient age

Dose for 1 reception

with various methods of drug administration

inside

(ml)

in an enema

(ml)

0-6 months

five

10

6-12 months

10

twenty

1 to 3 years old

fifteen

20-30

From 3 to 8 years old

twenty

30-40

8 years and older

20-30

40-50

Treatment of pyoinflammatory diseases with localized lesions should be carried out simultaneously both locally and by taking the drug inside.

In the case of treatment of the cavity of a purulent focus with chemical antiseptics, before using the bacteriophage, it must be washed with a sterile 0.9% sodium chloride solution.

In the treatment of ozena and scleroma, the drug is used to rinse the nasal cavity and mucous membrane of the upper respiratory tract, for injection into the sinuses (according to clinical indications), as well as in case of damage to the pharynx, larynx, trachea in the form of inhalation (without heating and using ultrasound). 

The dose of the drug for the treatment of the mucous membranes of the nose and upper respiratory tract is 10-20 ml. After washing the mucous membranes into the nasal cavity in turn, turundas moistened with the drug are introduced into each nasal passage and left for 1 hour. The procedure is repeated 2-3 times a day for 20-40 days. Since ozena and scleroma are chronic diseases, in order to prevent exacerbations, it is recommended to conduct 20-40 day courses of treatment once a year according to the above scheme.

In the treatment of tonsillitis, pharyngitis, laryngitis, the drug is used for rinsing the mouth and pharynx 3 times a day, 10-20 ml, the course of treatment is 7-10 days.

In the treatment of bronchitis, pneumonia, the drug is taken orally 3 times a day, 10-20 ml, and is also used in the form of aerosols and inhalations (without heating and using ultrasound), the course of treatment is 15-20 days.

In the treatment of otitis media, the drug is used for washing and injecting into the middle ear cavity, 2-5 ml 1-3 times a day. The course of treatment is 7-15 days.

In the treatment of sinus inflammation, the drug is used to flush the nasal cavity, nasopharynx and nasal sinuses in a dose of 5-10 ml and inject 2-3 ml into the sinuses. The procedure is repeated once daily for 7-10 days. In addition, the drug is injected into the nasal cavity in the form of turundas moistened with a bacteriophage, in turn, into each nasal passage and left for 0.5-1 hour. The procedure is repeated 3 times a day, the course of treatment is 7-15 days.

In the treatment of stomatitis and chronic periodontitis, the drug is used in the form of rinsing the oral cavity 3-4 times a day at a dose of 10-20 ml, as well as injecting turunda impregnated with Klebsiella bacteriophage into the periodontal pockets for 5-10 minutes, the course of treatment is 7-10 days ...

For conjunctivitis and keratoconjunctivitis, the drug is used 2-3 drops 4-5 times a day, the course of treatment is 5-7 days; with a purulent corneal ulcer - 4-5 drops per day for 7-10 days; with purulent iridocyclitis - 6-8 drops every 3 hours in combination with oral administration in therapeutic dosages for 7-10 days.

In case of abscesses after opening and removal of purulent contents, the drug is administered in an amount less than the volume of removed pus once daily, the course of treatment is 7-10 days.

In case of peritonitis and pleurisy, the drug is injected into the drained cavities - abdominal and pleural through drainage tubes once daily, 20-70 ml, the course of treatment is 10-15 days.

In osteomyelitis, the drug is injected into the wound cavity through turundas, drainages in an amount of 10-30 ml once daily, the course of treatment is 15-20 days.

In the treatment of wound suppuration, the drug is used in the form of irrigation, applications, dressings, introduction into the drainage at a dose of 5-50 ml, depending on the lesion focus, at least once a day, the course of treatment is 10-15 days.

In the treatment of purulent-inflammatory gynecological diseases (suppuration of wounds, endometritis, vulvitis, bartholinitis, colpitis, salpingo-oophoritis), the drug is used for irrigation, applications, injected into the cavity of wounds, vagina, uterus, 5-20 ml once a day for 7-10 days.

With cystitis, pyelonephritis, urethritis, the drug is taken orally in a therapeutic dose 3 times a day 1 hour before meals for 10-20 days. In the event that the cavity of the bladder or renal pelvis is drained, the drug is administered through a cystostomy or nephrostomy 1-3 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis, the course of treatment is 7-15 days.

With gastroenterocolitis, pancreatitis, cholecystitis, as well as intestinal dysbiosis, the bacteriophage is taken orally in age-specific dosages 3 times a day 1 hour before meals for 7-15 days (according to clinical indications). With indomitable vomiting, the drug is used in the form of high enemas 2-3 times a day, 20-40 ml. In case of intestinal dysbiosis, the drug can be used with preparations of normal flora.

For the prevention of nosocomial surgical infections, the drug is used to treat postoperative and freshly infected wounds in a dose of 5-50 ml, depending on the lesion, once daily for 5-7 days.

Use of the drug in children under 1 year of age (including premature babies)

With gastroenterocolitis, pneumonia and sepsis of newborns, the drug is used by mouth 2-3 times a day, 3-5 ml 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a gas tube or catheter) once daily at a dose of 5-10 ml. A combination of rectal (in the form of high enemas) and oral administration of the drug is possible. The course of treatment is 7-15 days (according to clinical indications). With a recurrent course of the disease, it is possible to repeat the course of treatment.

In order to prevent the occurrence of nosocomial infection in newborns, bacteriophage is used according to epidemic indications, 3-5 ml orally 3 times a day 30 minutes before feeding during the entire period of hospital stay.

In the treatment of omphalitis, pyoderma, infected wounds, the bacteriophage is used in the form of applications of 5-10 ml 2-3 times a day (a gauze cloth is moistened with a bacteriophage and applied to the umbilical wound or the affected area of ​​the skin) for 7-15 days.

The use of the drug does not exclude the use of other antibacterial and anti-inflammatory drugs.

Special instructions

The opening of vials and ampoules and the procedure for introducing the drug is carried out in strict observance of the rules of antiseptics.

If the integrity of the packaging and labeling is violated, the drug becomes cloudy, it is not used.

Release form

Solution for oral administration, local and external use

Storage conditions

In a dry, dark place at a temperature of 2-8 ° C

Shelf life

2 years

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